Rami A Al-Horani Selected Research

Factor XIa (Coagulation Factor XIa)

11/2020	Discovery of Benzyl Tetraphosphonate Derivative as Inhibitor of Human Factor Xia.
1/2020	Factor XI(a) inhibitors for thrombosis: an updated patent review (2016-present).
1/2016	Factor XIa inhibitors: A review of the patent literature.
3/2013	Discovery of allosteric modulators of factor XIa by targeting hydrophobic domains adjacent to its heparin-binding site.
2/2013	Sulfated pentagalloylglucoside is a potent, allosteric, and selective inhibitor of factor XIa.

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Rami A Al-Horani Research Topics

Disease

11	Hemorrhage 04/2022 - 02/2013
7	Thrombosis (Thrombus) 01/2022 - 01/2014
4	Inflammation (Inflammations) 05/2021 - 12/2020
4	Virus Diseases (Viral Diseases) 04/2021 - 01/2020
4	COVID-19 04/2021 - 01/2020
3	Infections 01/2021 - 01/2020
2	Thrombocytopenia (Thrombopenia) 04/2021 - 06/2019
2	Neoplasms (Cancer) 01/2020 - 08/2014
2	Venous Thrombosis (Deep-Vein Thrombosis) 12/2019 - 01/2018
2	Neoplasm Metastasis (Metastasis) 11/2014 - 08/2014
1	Thromboembolism 04/2022
1	Edema (Dropsy) 01/2022
1	Fibrosis (Cirrhosis) 04/2021
1	Critical Illness (Critically Ill) 01/2021
1	Stroke (Strokes) 01/2021
1	Coronavirus Infections 12/2020
1	Venous Thromboembolism 08/2020
1	Pathologic Processes 01/2020
1	Emphysema 01/2020
1	Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune) 06/2019
1	Liver Diseases (Liver Disease) 06/2019
1	Disseminated Intravascular Coagulation 06/2019
1	Herpes Simplex 08/2018
1	Colonic Neoplasms (Colon Cancer) 08/2014
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2014
1	Skeletal Abnormalities Mandibular Hypoplasia Auditory Canal Atresia Short Stature 03/2013

Drug/Important Bio-Agent (IBA)

10	AnticoagulantsIBA 04/2022 - 02/2013
5	Factor XIa (Coagulation Factor XIa)IBA 11/2020 - 02/2013
4	Pharmaceutical PreparationsIBA 04/2022 - 01/2016
3	Thrombin FDA Link 04/2022 - 12/2020
3	Heparin (Liquaemin)FDA LinkGeneric 04/2021 - 01/2018
3	GlycosaminoglycansIBA 08/2018 - 03/2013
2	FibrinIBA 01/2022 - 08/2020
2	Serine Proteases (Serine Protease)IBA 05/2021 - 01/2020
2	Proteinase-Activated ReceptorsIBA 04/2021 - 12/2020
2	VaccinesIBA 01/2021 - 07/2020
2	Proteins (Proteins, Gene)FDA Link 07/2020 - 01/2020
2	Factor XI (Plasma Thromboplastin Antecedent)IBA 01/2020 - 01/2018
2	SerpinsIBA 01/2020 - 01/2014
2	Peptide Hydrolases (Proteases)FDA Link 01/2018 - 01/2014
1	Factor Xa (Coagulation Factor Xa)IBA 04/2022
1	Factor IX (Coagulation Factor IX)FDA LinkGeneric 04/2022
1	Ethacrynic Acid (Etacrynic Acid)FDA Link 01/2022
1	DiureticsIBA 01/2022
1	TransglutaminasesIBA 01/2022
1	Leukocyte Elastase (Neutrophil Elastase)IBA 05/2021
1	argatroban (MPQA)FDA Link 04/2021
1	Antiviral Agents (Antivirals)IBA 04/2021
1	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 01/2021
1	Dipyridamole (Persantine)FDA LinkGeneric 01/2021
1	CytokinesIBA 01/2021
1	Factor Xa InhibitorsIBA 12/2020
1	Prothrombin (Factor II)IBA 12/2020
1	Factor XIIIaIBA 08/2020
1	CoagulantsIBA 01/2020
1	Viral ProteinsIBA 01/2020
1	ChemokinesIBA 01/2020
1	Enzyme Precursors (Zymogens)IBA 01/2020
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2020
1	EnzymesIBA 12/2019
1	Enoxaparin (Lovenox)FDA LinkGeneric 12/2019
1	Thromboplastin (Tissue Factor)IBA 12/2019
1	Therapeutic UsesIBA 06/2019
1	Thrombopoietin ReceptorsIBA 06/2019
1	fostamatinibIBA 06/2019
1	Pentamidine (NebuPent)FDA LinkGeneric 06/2019
1	ISIS 416858IBA 01/2018
1	Antifibrinolytic Agents (Antifibrinolytics)IBA 11/2014
1	Carrier Proteins (Binding Protein)IBA 03/2013
1	ElementsIBA 03/2013

Therapy/Procedure

6	Therapeutics 04/2021 - 01/2014
1	Knee Replacement Arthroplasty (Total Knee Replacement) 01/2018